Benign Prostatik Patolojilerde Regülatuvar T Hücrelerinin (Treg) Değerlendirilmesi: Pilot Çalışma

Objective: We aimed to evaluate the number and function of regulatory T (Treg) cells in peripheral blood prostate tissues patients with histopathologically diagnosed benign hyperplasia (BPH) asymptomatic chronic prostatitis.
 Material Methods: Blood histopathological data 19 (BPH=10, ACP=9) that underwent transurethral resection were evaluated. Treg cell count prostatic tissue flowcytometry, Forkhead box P3 (FOXP3) expression by reverse transcription polymerase chain reaction (PCR), IL-17 measurement samples ELISA performed. 
 Results: Flowcytometric analyses showed mean CD4+T FOXP3 levels both (CD4+T, p= 0.752; FOXP3, 1.000) 0.458; 0.590) higher BPH group compared prostatitis group. However this difference was not statistically significant. Similarly, also groups, but significant (p= 0.870). The PCR gene group, again there no between groups 0.116).
 Conclusion: Since found terms tissue, our study supports thesis these pathologies could be autoimmune inflammatory diseases.